Npn-1 Primes Limbs for Motion

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Npn-1 Primes Limbs for Motion

During neural development, the axons of sensory and motor neurons must extend over long distances—meters in some animals—to reach the most distant parts of the limbs. The axons of these neurons adhere tightly together to form spinal nerves that project over these distances to their peripheral targets. This process, called fasciculation, controls axon outgrowth and guidance. However, the underly...

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ژورنال

عنوان ژورنال: PLoS Biology

سال: 2011

ISSN: 1545-7885

DOI: 10.1371/journal.pbio.1001023